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Survival from colorectal cancer in Europe vs America	18 January 2005

		There are wide variations in diagnostic and surgical practice between Europe and the USA and survival differences in colorectal cancer although large, can be mostly attributable to differences in stage at diagnosis, reports January's issue of Gut.

Predicting outcomes for resection of ductal adenocarcinoma	18 January 2005

		Results of a study in January's British Journal of Cancer indicate that, in patients who have undergone potentially curative resection for ductal adenocarcinoma of the head of pancreas, the presence of a systemic inflammatory response predicts poor outcome.

Single stool blood test: poor screening for colorectal cancer	18 January 2005

		In people without symptoms for colorectal cancer, the single office-based fecal occult blood test misses advanced precancerous lesions 95% of the time and hence is a poor screening test, reports the most recent issue of Annals of Internal Medicine.

Discontinuation of pegylated interferon plus ribavirin therapy	17 January 2005

		Early discontinuation of 'ineffective' anti-viral therapy is unpopular with patients, reports the most recent issue of Alimentary Pharmacology and Therapeutics and further education regarding the cost-effectiveness will be needed if early discontinuation is to be accepted.

Detection of bowel polyps in hereditary polyposis syndromes	17 January 2005

		Capsule endoscopy may be of clinical value in selected patients with familial adenomatous polyposis, whereas in Peutz-Jeghers syndrome, capsule endoscopy could be used as first line surveillance procedure, reports January's American Journal of Gastroenterology.

Synbiotic therapy aids resolution of inflammation in ulcerative colitis	17 January 2005

		Research in January's issue of Gut finds that short term synbiotic treatment of active ulcerative colitis results in the improvement of the full clinical appearance of chronic inflammation in patients receiving this therapy.

Trends in ulcer diagnosis with high prevalence of H pylori	14 January 2005

		In an area with a high prevalence of H. pylori infection, the incidence of peptic ulcer is declining rapidly due to a reduction of H. pylori infection in the young and widespread use of proton-pump inhibitors, reports January's Alimentary Pharmacology and Therapeutics.

Red meat consumption increases risk of colorectal cancer	14 January 2005

		There is potential value in examining long-term meat consumption when assessing cancer risk, with evidence showing that prolonged high consumption of red and processed meat may increase the risk of cancer in the distal portion of the large intestine, reports this week's JAMA.

Children with early-onset inflammatory bowel disease	14 January 2005

		Research in January's Journal of Pediatrics reveals an age-related variation in the distribution of inflammatory bowel disease phenotype, with a high prevalence of isolated colonic disease in young children.

Patterns of alcohol consumption and H pylori infection	13 January 2005

		Results published in January's Alimentary Pharmacology and Therapeutics support suggestions that regular but moderate consumption of alcohol from various sources may facilitate elimination of H. pylori infection.

Impact of immunosuppressants on surgery for Crohn's	13 January 2005

		Although immunosuppressants have been used more frequently over the last 25 years, there has been no significant decrease in the need for surgery, or of intestinal complications of Crohn's disease, reports February's Gut.

Obliteration of portal-systemic shunts benefits patients	13 January 2005

		Obliteration of portal-systemic shunts followed by partial splenic artery embolization benefit patients with portal-systemic encephalopathy, reports the most recent issue of The American Journal of Gastroenterology.

Comparing 3 methods for open inguinal hernia repair	12 January 2005

		Results show that there is no clinically significant difference in postoperative pain and quality of life between the 3 types of mesh hernia repair: mesh plug repair, Prolene® Hernia System and the Lichtenstein method.

Chromoendoscopy is useful for surveillance of Barrett's	12 January 2005

		A report in January's issue The American Journal of Gastroenterology finds that the combination of crystal violet chromoendoscopy and pit pattern diagnosis is considered to be useful for the surveillance of short-segment Barrett's esophagus.

Anterior resection for veterans' rectal cancer: more common	12 January 2005

		Older age, lower co-morbidity score and lower hospital surgical volume are predictive of lower anterior resection, reports January's Alimentary Pharmacology and Therapeutics and the procedure is reported as being used more frequently over time.

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